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Zuclopenthixol dihydrochloride

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Specification

Cat. No.

SMD1769

Related Diseases

Schizophrenia

Product Name

Zuclopenthixol dihydrochloride

Size

Customizable

Price

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Description

Zuclopenthixol, also known as Cisordinol, Clopixol, Acuphase, zuclopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1962 by Lundbeck. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol is not approved for use in the United States. Zuclopenthixol has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but no affinity for cholinergic muscarine receptors. It has weak histamine (H1) receptor affinity and no α2-adrenoceptor blocking activity.

CAS Number

58045-23-1 (HCl)

Chemical Formula

C22H27Cl3N2OS

Exact Mass

472.09

Molecular Weight

473.88

Elemental Analysis

C, 55.76; H, 5.74; Cl, 22.44; N, 5.91; O, 3.38; S, 6.77

Synonym

Zuclopenthixol dihydrochloride; Zuclopenthixol HCl; alpha-Clopenthixol; Cisordinol; Clopenthixol; Zuclopenthixol; Cisordinol; cis-Clopenthixol; Clopixol;

IUPAC/Chemical Name

2-[4-[(3Z)-3-(2-Chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol dihydrochloride

InChi Key

LPWNZMIBFHMYMX-MHKBYHAFSA-N

InChi Code

InChI=1S/C22H25ClN2OS.2ClH/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26;;/h1-2,4-8,16,26H,3,9-15H2;2*1H/b18-5-;;

SMILES Code

ClC1=CC(/C2=C\CCN3CCN(CCO)CC3)=C(SC4=C2C=CC=C4)C=C1.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.