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Ziprasidone HCl

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Specification

Cat. No.

SMD570

Related Diseases

Bipolar Disorder

Related Diseases

Schizophrenia

Related Diseases

Depression

Product Name

Ziprasidone HCl

Size

200.0mg; 500.0mg; 1.0g

Price

Inquiry

Availability

2 Weeks

Description

Ziprazidone is approved for the treatment of schizophrenia, and acute mania and mixed states associated with bipolar disorder. Its intramuscular injection form is approved for acute agitation in schizophrenic patients for whom treatment with just ziprasidone is appropriate. The mechanism of action of ziprasidone, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been proposed that this drug's efficacy in schizophrenia is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) antagonism. As with other drugs having efficacy in bipolar disorder, the mechanism of action of ziprasidone in bipolar disorder is unknown.

CAS Number

122883-93-6 (HCl)

Chemical Formula

C21H22Cl2N4OS

Molecular Weight

449.394

Elemental Analysis

C, 56.13; H, 4.93; Cl, 15.78; N, 12.47; O, 3.56; S, 7.13

Synonym

CP88059; CP-88059; CP 88059; CP-88,059; CP-88,059-01; CP88059 mesylate; Ziprasidone mesylate, brand name: Geodon; Zeldox; Zipwell.

IUPAC/Chemical Name

5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one hydrochloride

InChi Key

NZDBKBRIBJLNNT-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H21ClN4OS.ClH/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21;/h1-4,11,13H,5-10,12H2,(H,23,27);1H

SMILES Code

O=C1NC2=C(C=C(CCN3CCN(C4=NSC5=CC=CC=C45)CC3)C(Cl)=C2)C1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.