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XAP044

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Specification

Cat. No.

SMD439

Related Diseases

Anxiety

Product Name

XAP044

Size

5.0mg; 10.0mg

Price

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Availability

2 Weeks

Description

XAP044 is a potent and selective mGlu7 antagonist (IC50 = 88 nM). It inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. XAP044 displays no effects on the LTP of mGlu7 deficient mice.

CAS Number

196928-50-4

Chemical Formula

C15H9IO4

Exact Mass

379.9546

Molecular Weight

380.14

Elemental Analysis

C, 47.39; H, 2.39; I, 33.38; O, 16.83

Synonym

XAP044; XAP 044; XAP-044

IUPAC/Chemical Name

7-hydroxy-3-(4-iodophenoxy)chromen-4-one

InChi Key

XXZKJJYWINSUMJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C15H9IO4/c16-9-1-4-11(5-2-9)20-14-8-19-13-7-10(17)3-6-12(13)15(14)18/h1-8,17H

SMILES Code

O=C1C(OC2=CC=C(I)C=C2)=COC3=C1C=CC(O)=C3

Appearance

White to beige solid powder.

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.