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VU6001966

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Specification

Cat. No.

SMD1256

Related Diseases

Depression

Product Name

VU6001966

Size

Customizable

Price

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Description

VU6001966 is a potent and selective mGlu2 inhibitor and Negative allosteric modulator. VU6001966 has a mGlu2 IC50 = 78 nM and mGlu3 IC50 > 30 μM. It exhibits excellent central nervous system (CNS) penetration and represents an exciting lead series for potential mGlu2 PET tracer development.

CAS Number

2009052-76-8

Chemical Formula

C17H15FN4O2

Exact Mass

326.1179

Molecular Weight

326.33

Elemental Analysis

C, 62.57; H, 4.63; F, 5.82; N, 17.17; O, 9.81

Synonym

VU6001966; VU-6001966; VU 6001966

IUPAC/Chemical Name

4-(4-fluorophenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide

InChi Key

SSSNPJKQBYVHBV-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H15FN4O2/c1-22-7-6-13(21-22)10-24-16-9-20-15(17(19)23)8-14(16)11-2-4-12(18)5-3-11/h2-9H,10H2,1H3,(H2,19,23)

SMILES Code

CN1C=CC(COC2=C(C3=CC=C(F)C=C3)C=C(C(N)=O)N=C2)=N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.