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VU 6010572

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Specification

Cat. No.

SMD1261

Related Diseases

Depression

Product Name

VU 6010572

Size

Customizable

Price

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Description

VU 6010572 is a negative allosteric modulator (NAM) for mGlu. VU 6010572 has an IC50 of 245 nM for mGlu3 with high selectivity among all mGlu receptors. VU 6010572 is highly CNS penetrant.

CAS Number

2126784-39-0

Chemical Formula

C20H18FNO3

Exact Mass

339.1271

Molecular Weight

339.37

Elemental Analysis

C, 70.78; H, 5.35; F, 5.60; N, 4.13; O, 14.14

Synonym

VU 6010572; VU-6010572; VU6010572

IUPAC/Chemical Name

(S)-1-(4-fluorophenyl)-4-(2-phenoxypropoxy)pyridin-2(1H)-one

InChi Key

AUMJXOXUSGIUCB-HNNXBMFYSA-N

InChi Code

InChI=1S/C20H18FNO3/c1-15(25-18-5-3-2-4-6-18)14-24-19-11-12-22(20(23)13-19)17-9-7-16(21)8-10-17/h2-13,15H,14H2,1H3/t15-/m0/s1

SMILES Code

FC(C=C1)=CC=C1N2C=CC(OC[C@H](C)OC3=CC=CC=C3)=CC2=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.