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UNC9994

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Specification

Cat. No.

SMD1735

Related Diseases

Schizophrenia

Product Name

UNC9994

Size

Customizable

Price

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Description

UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%). UNC9994 has robust in vivo antipsychotic drug-like activities. Functionally selective G protein-coupled receptor (GPCR) ligands, which differentially modulate canonical and noncanonical signaling, are extremely useful for elucidating key signal transduction pathways essential for both the therapeutic actions and side effects of drugs.

CAS Number

1354030-51-5

Chemical Formula

C21H22Cl2N2OS

Exact Mass

420.083

Molecular Weight

421.38

Elemental Analysis

C, 59.86; H, 5.26; Cl, 16.83; N, 6.65; O, 3.80; S, 7.61

Synonym

UNC9994, UNC 9994, UNC-9994

IUPAC/Chemical Name

5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole

InChi Key

URYZTMIOHYGTNJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H22Cl2N2OS/c22-18-4-1-3-17(21(18)23)15-7-10-25(11-8-15)9-2-12-26-16-5-6-20-19(13-16)24-14-27-20/h1,3-6,13-15H,2,7-12H2

SMILES Code

ClC1=CC=CC(C2CCN(CCCOC3=CC(N=CS4)=C4C=C3)CC2)=C1Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.