Related Diseases
Schizophrenia
Description
UNC9975 is a novel β-arrestin-biased D2R agonist. UNC9975 is an analog of aripiprazole and is a β-arrestin–biased dopamine D2 receptor ligand. Functionally selective, β-arrestin-biased D(2)R ligands represent valuable chemical probes for further investigations of D(2)R signaling in health and disease.
Chemical Formula
C23H28Cl2N4O2
Elemental Analysis
C, 59.61; H, 6.09; Cl, 15.30; N, 12.09; O, 6.91
Synonym
UNC9975, UNC-9975, UNC9975
IUPAC/Chemical Name
7-{4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy}-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one
InChi Key
JQSRFMXTGAVHIR-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H28Cl2N4O2/c24-18-5-3-6-19(22(18)25)29-13-4-12-28(14-15-29)11-1-2-16-31-21-10-8-17-7-9-20(30)26-23(17)27-21/h3,5-6,8,10H,1-2,4,7,9,11-16H2,(H,26,27,30)
SMILES Code
O=C1NC2=NC(OCCCCN3CCN(C4=CC=CC(Cl)=C4Cl)CCC3)=CC=C2CC1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001