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Ulotaront HCl

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Specification

Cat. No.

SMD1722

Related Diseases

Schizophrenia

Related Diseases

Depression

Product Name

Ulotaront HCl

Size

5.0mg; 10.0mg

Price

Inquiry

Availability

2 Weeks

Description

Ulotaront, also known as SEP-363856, and SEP-856, is a TAAR1/5-HT1A agonist. Ulotaront interacts with a small, common set of conserved residues within the TAAR1 and 5HT1A ligand-binding domain. Ulotaront is a compound of high solubility, high permeability, and low binding to plasma proteins. Ulotaront metabolism is mediated via both NADPH-dependent and NADPH-independent pathways, with CYP2D6 as the major metabolizing enzyme. Ulotaront is a promising agent for the treatment of schizophrenia with an apparent benign safety profile, which might provide a much-needed new and different treatment option for various domains of schizophrenia.

CAS Number

1310422-41-3 (HCl)

Chemical Formula

C9H14ClNOS

Exact Mass

183.0718

Molecular Weight

219.73

Elemental Analysis

C, 49.20; H, 6.42; Cl, 16.13; N, 6.37; O, 7.28; S, 14.59

Synonym

Ulotaront HCl; Ulotaront hydrochloride; Ulotaront; SEP-856; SEP856; SEP 856; SEP-363856; SEP 363856; SEP363856;

IUPAC/Chemical Name

(7S)-4,7-Dihydro-N-methyl-5H-thieno[2,3-c]pyran-7-methanamine hydrochloride

InChi Key

JRDQGVVFSHRVTL-QRPNPIFTSA-N

InChi Code

InChI=1S/C9H13NOS.ClH/c1-10-6-8-9-7(2-4-11-8)3-5-12-9;/h3,5,8,10H,2,4,6H2,1H3;1H/t8-;/m0./s1

SMILES Code

CNC[C@H]1C2=C(C=CS2)CCO1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.