Related Diseases
Schizophrenia
Product Name
Trihexyphenidyl hydrochloride
Description
Trihexyphenidyl Hydrochloride is the hydrochloride salt form of trihexyphenidyl, a synthetic, substituted piperidine with Para sympatholytic activity used mostly in Parkinson's disease. Trihexyphenidyl hydrochloride antagonizes activities of acetylcholine via muscarinic receptors. This balances the cholinergic and dopaminergic activity in the basal ganglia leading to an improvement of classic Parkinson symptoms such as rigidity and tremor. In addition, trihexyphenidyl hydrochloride exerts a direct antispasmodic effect on smooth muscle.
Chemical Formula
C20H32ClNO
Elemental Analysis
C, 71.09; H, 9.55; Cl, 10.49; N, 4.14; O, 4.73
Synonym
Trihexyphenidyl hydrochloride; Trihexyphenidyl-hydrochloride; Benzhexol hydrochloride;
IUPAC/Chemical Name
1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
InChi Key
QDWJJTJNXAKQKD-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H
SMILES Code
OC(C1CCCCC1)(c2ccccc2)CCN3CCCCC3.Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001