Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

TP0473292

Inquiry

Specification

Cat. No.

SMD1236

Related Diseases

Depression

Product Name

TP0473292

Size

Customizable

Price

Inquiry

Description

TP0473292 is an adamantane carboxylic acid ester prodrug of TP0178894, a metabotropic glutamate 2 and 3 receptor antagonist for use as an antidepressant. TP0473292 has undergone phase 1 clinical trials for treatment of depression.

CAS Number

N/A

Chemical Formula

C28H33F2NO7

Exact Mass

533.2225

Molecular Weight

533.57

Elemental Analysis

C, 63.03; H, 6.23; F, 7.12; N, 2.63; O, 20.99

Synonym

TP0473292; TP 0473292; TP-0473292

IUPAC/Chemical Name

(1R,2R,3R,5R,6R)-2-(((S)-1-((adamantane-1-carbonyl)oxy)ethoxy)carbonyl)-2-amino-6-fluoro-3-((4-fluorobenzyl)oxy)bicyclo[3.1.0]hexane-6-carboxylic acid

InChi Key

OCKJWSRXCCMMEI-AHGQKZNCSA-N

InChi Code

InChI=1S/C28H33F2NO7/c1-14(37-24(34)26-10-16-6-17(11-26)8-18(7-16)12-26)38-25(35)28(31)21(9-20-22(28)27(20,30)23(32)33)36-13-15-2-4-19(29)5-3-15/h2-5,14,16-18,20-22H,6-13,31H2,1H3,(H,32,33)/t14-,16?,17?,18?,20+,21+,22-,26?,27+,28-/m0/s1

SMILES Code

O=C([C@@]1(F)[C@]2([H])C[C@@H](OCC3=CC=C(F)C=C3)[C@@](N)(C(O[C@H](OC(C45CC6CC(C5)CC(C6)C4)=O)C)=O)[C@]12[H])O

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.