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Tiagabine hydrochloride

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Specification

Cat. No.

SMD588

Related Diseases

Bipolar Disorder

Related Diseases

Anxiety

Product Name

Tiagabine hydrochloride

Size

100.0mg; 250.0mg; 500.0mg

Price

Inquiry

Availability

2 Weeks

Description

Tiagabine is an anti-convulsive medication. The medication is also utilized in the treatment of panic disorder, as are a few other anticonvulsants. Tiagabine increases the level of gamma aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system by blocking the GABA transporter and hence is classified as a GABA reuptake inhibitor.

CAS Number

145821-59-6 (HCl)

Chemical Formula

C20H26ClNO2S2

Molecular Weight

412.003

Elemental Analysis

C, 58.31; H, 6.36; Cl, 8.60; N, 3.40; O, 7.77; S, 15.56

Synonym

NO-329; NO329; NO 329; NNC-05-0328; NO-05-0328; Tiagabine hydrochloride; brand name Gabitril

IUPAC/Chemical Name

(R)-1-(4,4-bis(3-methylthiophen-2-yl)but-3-en-1-yl)piperidine-3-carboxylic acid hydrochloride

InChi Key

YUKARLAABCGMCN-PKLMIRHRSA-N

InChi Code

InChI=1S/C20H25NO2S2.ClH/c1-14-7-11-24-18(14)17(19-15(2)8-12-25-19)6-4-10-21-9-3-5-16(13-21)20(22)23;/h6-8,11-12,16H,3-5,9-10,13H2,1-2H3,(H,22,23);1H/t16-;/m1./s1

SMILES Code

CC1=C(SC=C1)C(=CCCN2CCC[C@H](C2)C(=O)O)C3=C(C=CS3)C.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.