Related Diseases
Schizophrenia
Description
Terguride is 5-HT receptor antagonist. Terguride is a drug used to treat hyperprolactinemia that antagonizes 5-HT2A and 5-HT2B and activates dopamine receptors. It has also been extensively studied for the treatment of PAH.
Chemical Formula
C20H28N4O
Elemental Analysis
C, 70.56; H, 8.29; N, 16.46; O, 4.70
Synonym
Terguride; Dironyl; trans-Dihydrolisuride; trans Dihydrolisuride;
IUPAC/Chemical Name
1,1-diethyl-3-((6aR,9S,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)urea
InChi Key
JOAHPSVPXZTVEP-YXJHDRRASA-N
InChi Code
InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1
SMILES Code
[H][C@]12C[C@H](N([H])C(N(CC)CC)=O)CN(C)[C@]1([H])CC3=CN([H])C4=CC=CC2=C34
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001