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TC-2153 HCl

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Specification

Cat. No.

SMD1217

Related Diseases

Depression

Product Name

TC-2153 HCl

Size

5.0mg; 25.0mg

Price

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Availability

2 Weeks

Description

TC-2153 is a potent inhibitor of STEP (STriatal-Enriched protein tyrosine Phosphatase) that forms a reversible covalent bond with the catalytic cysteine in STEP. TC-2153 increases tyrosine phosphorylation of STEP substrates ERK1/2, Pyk2, and GluN2B in cell cultures. TC-2153 improves cognitive function in transgenic AD mice.

CAS Number

1381769-23-8 (HCl)

Chemical Formula

C7H5ClF3NS5

Exact Mass

354.867

Molecular Weight

355.8692

Elemental Analysis

C, 23.63; H, 1.42; Cl, 9.96; F, 16.02; N, 3.94; S, 45.04

Synonym

TC-2153; TC 2153; TC2153;

IUPAC/Chemical Name

8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride

InChi Key

PYFSCYSDPQMEGZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C7H4F3NS5.ClH/c8-7(9,10)3-1-4(11)6-5(2-3)12-14-16-15-13-6;/h1-2H,11H2;1H

SMILES Code

NC1=C2SSSSSC2=CC(C(F)(F)F)=C1.[H]Cl

Appearance

Solid powder

Purity

>95 % (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.