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TAS-109

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Specification

Cat. No.

SMD393

Related Diseases

Anxiety

Product Name

TAS-109

Size

10.0mg; 50.0mg; 100.0mg

Price

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Availability

2 Weeks

Description

TAS-109, also known as DFP-10917 and CNDAC, is an analogue of the nucleoside deoxycytidine with potential antineoplastic activity. Nucleoside analogue TAS-109 is incorporated into DNA and directly inhibits the activity of DNA polymerase, which may result in inhibition of DNA replication and cell cycle arrest in the S and G2/M phases, DNA fragmentation, and tumor cell apoptosis.

CAS Number

135598-68-4

Chemical Formula

C10H12N4O4

Exact Mass

252.08585

Molecular Weight

252.22668

Elemental Analysis

C, 47.62; H, 4.80; N, 22.21; O, 25.37

Synonym

TAS109; TAS109; TAS 109; DFP-10917; DFP 10917; DFP10917; CNDAC; Radgocitabine

IUPAC/Chemical Name

(2R,3S,4S,5R)-2-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolane-3-carbonitrile

InChi Key

DCYBPMFXJCWXNB-JWIUVKOKSA-N

InChi Code

InChI=1S/C10H12N4O4/c11-3-5-8(16)6(4-15)18-9(5)14-2-1-7(12)13-10(14)17/h1-2,5-6,8-9,15-16H,4H2,(H2,12,13,17)/t5-,6+,8-,9+/m0/s1

SMILES Code

N#C[C@@H]1[C@H](N2C=CC(N)=NC2=O)O[C@H](CO)[C@H]1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>5 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.