Related Diseases
Depression
Description
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induced Ca2+ influx in hGluA1i-expressing CHO cells through structural interference at Ser743 in GluA1,
Chemical Formula
C19H23N3O3S
Elemental Analysis
C, 61.10; H, 6.21; N, 11.25; O, 12.85; S, 8.58
Synonym
TAK-653; TAK653; TAK 653; NBI-1065845; NBI1065845; NBI 1065845; osavampator
IUPAC/Chemical Name
9-(4-(cyclohexyloxy)phenyl)-7-methyl-3,4-dihydropyrazino[2,1-c][1,2,4]thiadiazine 2,2-dioxide
InChi Key
PXJBHEHFVQVDDS-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H23N3O3S/c1-14-13-22-11-12-26(23,24)21-19(22)18(20-14)15-7-9-17(10-8-15)25-16-5-3-2-4-6-16/h7-10,13,16H,2-6,11-12H2,1H3
SMILES Code
CC1=CN(CC2)C(C(C3=CC=C(OC4CCCCC4)C=C3)=N1)=NS2(=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001