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SZ-3

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Specification

Cat. No.

SMD1719

Related Diseases

Schizophrenia

Product Name

SZ-3

Size

Customizable

Price

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Description

SZ-3 is a first-in-class small-molecule inhibitor of cofilin to target secondary complications of ICH, mainly neuroinflammation. SZ-3 showed no effect on neuronal/microglial survival but prevented microglia from LPS-induced inflammation by decreasing NO and preventing neurotoxicity. and showed anti-inflammatory activities.

CAS Number

25477

Chemical Formula

C29H37N3O3

Exact Mass

475.2835

Molecular Weight

475.63

Elemental Analysis

C, 73.23; H, 7.84; N, 8.83; O, 10.09

Synonym

SZ3, sz-3, sz3

IUPAC/Chemical Name

1-(4-(Bis(5-(tert-butyl)-2-hydroxybenzyl)amino)phenyl)urea

InChi Key

OUKWSSCBNGZGDW-UHFFFAOYSA-N

InChi Code

InChI=1S/C29H37N3O3/c1-28(2,3)21-7-13-25(33)19(15-21)17-32(24-11-9-23(10-12-24)31-27(30)35)18-20-16-22(29(4,5)6)8-14-26(20)34/h7-16,33-34H,17-18H2,1-6H3,(H3,30,31,35)

SMILES Code

O=C(N)NC1=CC=C(N(CC2=CC(C(C)(C)C)=CC=C2O)CC3=CC(C(C)(C)C)=CC=C3O)C=C1

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.