Related Diseases
Depression
Size
5.0mg; 10.0mg; 25.0mg; 50.0mg
Description
Suritozole, also known as MDL-26479, is an investigational cognition enhancer. It acts as a partial inverse agonist at the benzodiazepine receptor site on the GABAA ion channel complex, but does not have either anxiogenic or convulsant effects, unlike other BZD inverse agonists such as DMCM. It was investigated for the treatment of depression and Alzheimer's disease, but clinical development seems to have been discontinued.
Chemical Formula
C10H10FN3S
Molecular Weight
223.2694
Elemental Analysis
C, 53.80; H, 4.51; F, 8.51; N, 18.82; S, 14.36
Synonym
MDL-26479; MDL 26479; MDL26479; Suritozole
IUPAC/Chemical Name
2,4-Dihydro-2,4-dimethyl-5-(3-fluorophenyl)-3H-1,2,4-triazole-3-thione
InChi Key
IWDUZEHNLHFBRZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H10FN3S/c1-13-9(12-14(2)10(13)15)7-4-3-5-8(11)6-7/h3-6H,1-2H3
SMILES Code
S=C1N(C)N=C(C2=CC=CC(F)=C2)N1C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001