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SRA880 malonate

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Specification

Cat. No.

SMD1175

Related Diseases

Depression

Product Name

SRA880 malonate

Size

Customizable

Price

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Description

SRA880 is a non-peptide somatostatin sst(1) receptor antagonist. SRA880 displayed significantly lower affinity for the other human recombinant somatostatin receptors ( pK(d) < or = 6.0) or a wide range of neurotransmitter receptors, except for the human dopamine D4 receptors. SRA880 positively modulates release of endogenous SRIF, was found to synergize with imipramine in causing antidepressant-like effects in the tail suspension test.

CAS Number

573984-99-3 (malonate)

Chemical Formula

C29H36N4O8

Molecular Weight

568.62

Elemental Analysis

C, 61.26; H, 6.38; N, 9.85; O, 22.51

Synonym

NVP-SRA880; NVP SRA880; NVPSRA880; NVP-SRA 880; NVP-SRA-880; SRA880; Obelin; SRA-880; SRA 880;

IUPAC/Chemical Name

[(3R,4aR,10aR)-6-Methoxy-1-methyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinolin-3-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone Malonate

InChi Key

ACSWUHCQQFGYBZ-GIEJAJRFSA-N

InChi Code

InChI=1S/C26H32N4O4.C3H4O4/c1-27-17-20(14-19-15-23-18(16-24(19)27)4-3-5-25(23)34-2)26(31)29-12-10-28(11-13-29)21-6-8-22(9-7-21)30(32)33;4-2(5)1-3(6)7/h3-9,19-20,24H,10-17H2,1-2H3;1H2,(H,4,5)(H,6,7)/t19-,20-,24-;/m1./s1

SMILES Code

O=C([C@H]1CN(C)[C@]2([H])CC3=CC=CC(OC)=C3C[C@@]2([H])C1)N4CCN(C5=CC=C([N+]([O-])=O)C=C5)CC4.O=C(O)CC(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.03.00

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.