Description
SR-10067 is a selective Rev-Erbα/β agonist that increases wakefulness, reduces REM and slow wave sleep in vivo. It also reduces anxiety-like behavior, is cell permeable, and is brain penetrant.
Chemical Formula
C31H31NO3
Elemental Analysis
C, 79.97; H, 6.71; N, 3.01; O, 10.31
Synonym
SR-10067, SR10067, SR 10067
IUPAC/Chemical Name
[3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone
InChi Key
MOPAGKWBFUICQT-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H31NO3/c1-31(2,3)35-27-17-15-26(16-18-27)34-21-25-19-23-10-4-5-11-24(23)20-32(25)30(33)29-14-8-12-22-9-6-7-13-28(22)29/h4-18,25H,19-21H2,1-3H3
SMILES Code
O=C(N1CC2=C(C=CC=C2)CC1COC3=CC=C(OC(C)(C)C)C=C3)C4=C5C=CC=CC5=CC=C4
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001