Related Diseases
Schizophrenia
Description
Spiperone is a antipsychotic that has been used to treat schizophrenia. Additionally, spiperone was identified by compound screening to be an activator of Ca2+ activated Cl− channels (CaCCs), thus a potential target for therapy of cystic fibrosis.
CAS Number
749-02-0 (free base)
Chemical Formula
C23H26FN3O2
Elemental Analysis
C, 69.85; H, 6.63; F, 4.80; N, 10.63; O, 8.09
Synonym
Spiperone; E 525; E-525; E525; R 5147; R-5147; R5147; NSC 170983; NSC-170983; NSC170983;
IUPAC/Chemical Name
8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
InChi Key
DKGZKTPJOSAWFA-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
SMILES Code
O=C1NCN(C2=CC=CC=C2)C13CCN(CCCC(C4=CC=C(F)C=C4)=O)CC3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.03.00