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SPDB crosslinker

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Specification

Cat. No.

SMD1199

Related Diseases

Depression

Product Name

SPDB crosslinker

Size

10.0mg; 25.0mg; 100.0mg; 500.0mg; 1.0g; 2.0g; 10.0g

Price

Inquiry

Availability

2 Weeks

Description

SPDB is useful heterobifunctional cross-linker, which is widely used to conjugate a small molecule drug to a targeted carrier (such as antibody, enzyme, protein and polymer). SPDB can be used to make ADC (antobody drug conjugate. Conjugated to antibodies utilizing disulfide linkers: anti-EGFR-SPDB-DM4 has been widely used.

CAS Number

115088-06-7

Chemical Formula

C13H14N2O4S2

Exact Mass

326.0395

Molecular Weight

326.385

Elemental Analysis

C, 47.84; H, 4.32; N, 8.58; O, 19.61; S, 19.65

Synonym

SPDB, SPDB disulfide heterobifunctional cross-linker.

IUPAC/Chemical Name

N-Succinimidyl 4-(2-pyridyldithio)butanoate

InChi Key

JSHOVKSMJRQOGY-UHFFFAOYSA-N

InChi Code

InChI=1S/C13H14N2O4S2/c16-11-6-7-12(17)15(11)19-13(18)5-3-9-20-21-10-4-1-2-8-14-10/h1-2,4,8H,3,5-7,9H2

SMILES Code

O=C(ON1C(CCC1=O)=O)CCCSSC2=NC=CC=C2

Appearance

Fluffy white solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.