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Smilagenin

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Specification

Cat. No.

SMD1675

Related Diseases

Schizophrenia

Product Name

Smilagenin

Size

10.0mg; 50.0mg; 100.0mg

Price

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Availability

2 Weeks

Description

Smilagenin, also known as PYM50028, is an orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease.

CAS Number

126-18-1

Chemical Formula

C27H44O3

Exact Mass

416.329

Molecular Weight

416.646

Elemental Analysis

C, 77.84; H, 10.65; O, 11.52

Synonym

Smilagenin; PYM50028; PYM 50028; AI3-44895; Cogane

IUPAC/Chemical Name

(25R)-5beta-Spirostan-3beta-ol

InChi Key

GMBQZIIUCVWOCD-UQHLGXRBSA-N

InChi Code

InChI=1S/C27H44O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28H,5-15H2,1-4H3/t16-,17+,18-,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

SMILES Code

[H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC[C@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.