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SM-21 maleate

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Specification

Cat. No.

SMD1171

Related Diseases

Depression

Product Name

SM-21 maleate

Size

Customizable

Price

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Description

SM-21 is a potent and selective sigma(2) antagonist. SM-21 is a tropane analogue with high affinity and selectivity for sigma(2) receptor subtype. SM 21 attenuates the convulsive and locomotor stimulatory effects of cocaine in mice. (+/-)-SM 21 may be a suitable lead compound for developing sigma2-selective ligands.

CAS Number

155058-71-2 (racemic free base)

Chemical Formula

C18H24ClNO3

Exact Mass

337.1445

Molecular Weight

337.84

Elemental Analysis

C, 63.99; H, 7.16; Cl, 10.49; N, 4.15; O, 14.21

Synonym

SM 21; SM21; SM-21; (±)-SM21; SM-21 maleate; SM-21 racemate maleate,

IUPAC/Chemical Name

(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-(4-chlorophenoxy)butanoate

InChi Key

WTPAXDRULIZRDJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H24ClNO3/c1-3-17(22-15-8-4-12(19)5-9-15)18(21)23-16-10-13-6-7-14(11-16)20(13)2/h4-5,8-9,13-14,16-17H,3,6-7,10-11H2,1-2H3

SMILES Code

CCC(OC1=CC=C(Cl)C=C1)C(O[C@H]2C[C@H](N3C)CC[C@H]3C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.