Siramesine HCl

More efficient, faster and cheaper. Ace Therapeutics are trustworthy.

sale

Siramesine HCl

Specification
Cat. No.
SMD1192
Related Diseases
Depression
Product Name
Siramesine HCl
Size
100.0mg
Price
Inquiry
Availability
2 Weeks
Description
Siramesine, also known as Lu-28-179, is a potent sigma-2 receptor agonist. Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Siramesine involves lysosomal leakage and oxidative stress.
CAS Number
224177-60-0 (HCl)
Chemical Formula
C30H32ClFN2O
Molecular Weight
491.0474
Elemental Analysis
C, 73.38; H, 6.57; Cl, 7.22; F, 3.87; N, 5.70; O, 3.26
Synonym
Siramesine; Siramesine HCl; Siramesine hydrochloride; Lu-28-179; Lu 28-179; Lu28-179; Lu-28179; Lu 28179; Lu28179.
IUPAC/Chemical Name
1'-(4-(1-(4-fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4'-piperidine] hydrochloride
InChi Key
ILSRGIFRZZSGPN-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H31FN2O.ClH/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30;/h1-4,8-15,21H,5-7,16-20,22H2;1H
SMILES Code
FC1=CC=C(N2C=C(CCCCN3CCC4(CC3)OCC5=CC=CC=C45)C6=C2C=CC=C6)C=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Enter Your Email to Subscribe

Enter your E-mail and receive the latest news from us

Copyright © Ace Therapeutics. All Rights Reserved.
Top