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Sintamil

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Specification

Cat. No.

SMD1190

Related Diseases

Depression

Product Name

Sintamil

Size

Customizable

Price

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Description

Sintamil or Nitroxazepine is a tricyclic antidepressant (TCA) which was introduced by Ciba-Geigy (now Novartis) for the treatment of depression in India in 1982. It is also indicated for the treatment of nocturnal enuresis. Nitroxazepine acts as a serotonin-norepinephrine reuptake inhibitor and has similar effects to imipramine, but with certain advantages, such as lower anticholinergic side effects.

CAS Number

16398-39-3

Chemical Formula

C18H20ClN3O4

Exact Mass

377.1142

Molecular Weight

377.83

Elemental Analysis

C, 57.22; H, 5.34; Cl, 9.38; N, 11.12; O, 16.94

Synonym

Sintamil; Ciba2330-Go; Ciba-2330-Go; Ciba 2330-Go

IUPAC/Chemical Name

10-(3-(Dimethylamino)propyl)-2-nitrodibenz(b,f)(1,4)oxazepin-11(10H)-one monohydrochloride

InChi Key

QQYWZPWIDBROOG-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H19N3O4.ClH/c1-19(2)10-5-11-20-15-6-3-4-7-17(15)25-16-9-8-13(21(23)24)12-14(16)18(20)22;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

SMILES Code

O=C1N(CCCN(C)C)C2=CC=CC=C2OC3=CC=C([N+]([O-])=O)C=C13.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.