Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Setiptiline maleate

Inquiry

Specification

Cat. No.

SMD1676

Related Diseases

Schizophrenia

Related Diseases

Depression

Product Name

Setiptiline maleate

Size

Customizable

Price

Inquiry

Description

Setiptiline, also known as MO 8282 and teciptiline, is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). It was launched in 1989 for the treatment of depression in Japan by Mochida. Setiptiline acts as a norepinephrine reuptake inhibitor,[3] α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.

CAS Number

85650-57-3 (maleate); 57262-94-9 (free base)

Chemical Formula

C23H23NO4

Molecular Weight

377.44

Elemental Analysis

C, 73.19; H, 6.14; N, 3.71; O, 16.96

Synonym

MO 8282; MO8282; MO-8282; BRN 1650422; BRN-1650422; BRN1650422; teciptiline; Setiptiline maleate; trade name Tecipul.

IUPAC/Chemical Name

2,3,4,9-Tetrahydro-2-methyl-1H-dibenzo(3,4:6,7)cyclohepta(1,2-c)pyridine maleate

InChi Key

AVPIBVPBCWBXIU-BTJKTKAUSA-N

InChi Code

InChI=1S/C19H19N.C4H4O4/c1-20-11-10-18-16-8-4-2-6-14(16)12-15-7-3-5-9-17(15)19(18)13-20;5-3(6)1-2-4(7)8/h2-9H,10-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES Code

CN1CCC(C2=CC=CC=C2CC3=CC=CC=C34)=C4C1.O=C(O)/C=C\C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.