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SB649868

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Specification

Cat. No.

SMD1325

Related Diseases

Insomnia

Product Name

SB649868

Size

100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

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Availability

2 Weeks

Description

SB649868, also known as GSK-649868, is an orexin receptor antagonist potentially for the treatment of insomnia and sleep disorder. SB-649868 promotes and maintains sleep in men with primary insomnia. SB-649868 may be a potentially effective and well-tolerated treatments for patients with sleep disorders.

CAS Number

380899-24-1

Chemical Formula

C26H24FN3O3S

Exact Mass

477.1522

Molecular Weight

477.5544

Elemental Analysis

C, 65.39; H, 5.07; F, 3.98; N, 8.80; O, 10.05; S, 6.71

Synonym

GSK-649868; GSK-649868; GSK649868; SB649868; SB-649868; SB 649868.

IUPAC/Chemical Name

(S)-N-((1-(5-(4-fluorophenyl)-2-methylthiazole-4-carbonyl)piperidin-2-yl)methyl)benzofuran-4-carboxamide

InChi Key

ZJXIUGNEAIHSBI-IBGZPJMESA-N

InChi Code

InChI=1S/C26H24FN3O3S/c1-16-29-23(24(34-16)17-8-10-18(27)11-9-17)26(32)30-13-3-2-5-19(30)15-28-25(31)21-6-4-7-22-20(21)12-14-33-22/h4,6-12,14,19H,2-3,5,13,15H2,1H3,(H,28,31)/t19-/m0/s1

SMILES Code

O=C(C1=C2C=COC2=CC=C1)NC[C@H]3N(C(C4=C(C5=CC=C(F)C=C5)SC(C)=N4)=O)CCCC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.