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SB357134

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Specification

Cat. No.

SMD1689

Related Diseases

Schizophrenia

Product Name

SB357134

Size

Customizable

Price

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Description

SB357134 is a potent, selective and orally active 5-HT6 receptor antagonist. SB-357134 and other 5-HT6 antagonists show nootropic effects in animal studies, and have been proposed as potential novel treatments for cognitive disorders such as schizophrenia and Alzheimer's disease.

CAS Number

219963-52-7

Chemical Formula

C17H18Br2FN3O3S

Exact Mass

520.942

Molecular Weight

523.22

Elemental Analysis

C, 39.03; H, 3.47; Br, 30.54; F, 3.63; N, 8.03; O, 9.17; S, 6.13

Synonym

SB357134; SB 357134; SB-357134.

IUPAC/Chemical Name

N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(piperazin-1-yl)benzene-1-sulfonamide

InChi Key

BLWHAZZXRHTFJE-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H18Br2FN3O3S/c1-26-16-3-2-12(10-15(16)23-6-4-21-5-7-23)27(24,25)22-14-9-11(18)8-13(20)17(14)19/h2-3,8-10,21-22H,4-7H2,1H3

SMILES Code

O=S(C1=CC=C(OC)C(N2CCNCC2)=C1)(NC3=CC(Br)=CC(F)=C3Br)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.