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SB 243213 Dihydrochloride

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Specification

Cat. No.

SMD405

Related Diseases

Anxiety

Product Name

SB 243213 Dihydrochloride

Size

Customizable

Price

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Description

SB 243213 dihydrochloride is a selective 5-HT2C inverse agonist (pKb = 9.8). It displays selectivity over other 5-HT2 subtypes (pKi values are 6.8, 7.0 and 9.0 for 5-HT2A, 5-HT2B and 5-HT2C respectively); also exhibits >100-fold selectivity over 50 other receptors, ion channels and enzymes.

CAS Number

200940-23-4 (HCl)

Chemical Formula

C22H21Cl2F3N4O2

Molecular Weight

501.33

Elemental Analysis

C, 52.71; H, 4.22; Cl, 14.14; F, 11.37; N, 11.18; O, 6.38

Synonym

SB 243213; SB-243213; SB243213; SB 243213 Dihydrochloride; SB 243213 DiHCl.

IUPAC/Chemical Name

2,3-Dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-1H-Indole-1-carboxamide dihydrochloride

InChi Key

UKMTYUXWLKQDNT-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H19F3N4O2.2ClH/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2;;/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30);2*1H

SMILES Code

O=C(N1CCC2=C1C=C(C(F)(F)F)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.