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Ro60-0175 free base

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Specification

Cat. No.

SMD340

Related Diseases

Anxiety

Product Name

Ro60-0175 free base

Size

50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

Inquiry

Availability

2 Weeks

Description

Ro60-0175 is a potent and selective SR-2 agonist. It shows selectivity for the 5-HT2C subtype (pKi values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). Ro60-0175 acts as a potent and selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, and little or no affinity at other receptors.

CAS Number

169675-08-5 (free base)

Chemical Formula

C11H12ClFN2

Exact Mass

226.0673

Molecular Weight

226.6794

Elemental Analysis

C, 58.29; H, 5.34; Cl, 15.64; F, 8.38; N, 12.36

Synonym

Ro60-0175; Ro-60-0175; Ro 60-0175; Ro600175; Ro-600175; Ro 600175;

IUPAC/Chemical Name

(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine

InChi Key

XJJZQXUGLLXTHO-ZETCQYMHSA-N

InChi Code

InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1

SMILES Code

C[C@H](N)CN1C=CC2=C1C=C(Cl)C(F)=C2

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.