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RO5166017 HCl

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Specification

Cat. No.

SMD1679

Related Diseases

Schizophrenia

Related Diseases

Depression

Product Name

RO5166017 HCl

Size

Customizable

Price

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Description

RO-5166017 is a potent and selective agonist for the trace amine-associated receptor 1, with no significant activity at other targets. This is important for the study of the TAAR1 receptor, as while numerous other compounds are known which act as TAAR1 agonists, such as methamphetamine, MDMA and 3-iodothyronamine, all previously known TAAR1 agonists are either weak and rapidly metabolized (endogenous ligands), or have strong pharmacological activity at other targets (amphetamines, thyronamines), making it very difficult to assess which effects are due to TAAR1 activation.

CAS Number

To be determined

Chemical Formula

C12H18ClN3O

Molecular Weight

255.75

Elemental Analysis

C, 56.36; H, 7.09; Cl, 13.86; N, 16.43; O, 6.26

Synonym

RO5166017 HCl; RO-5166017 HCl; RO 5166017 HCl; RO5166017 hydrochloride; RO-5166017 hydrochloride; RO 5166017 hydrochloride

IUPAC/Chemical Name

(S)-4-((ethyl(phenyl)amino)methyl)-4,5-dihydrooxazol-2-amine hydrochloride

InChi Key

XPJNPSWDRPQMRX-PPHPATTJSA-N

InChi Code

1S/C12H17N3O.ClH/c1-2-15(11-6-4-3-5-7-11)8-10-9-16-12(13)14-10;/h3-7,10H,2,8-9H2,1H3,(H2,13,14);1H/t10-;/m0./s1

SMILES Code

NC1=N[C@@H](CN(CC)C2=CC=CC=C2)CO1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.