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Ro 60-0175 fumarate

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Specification

Cat. No.

SMD365

Related Diseases

Anxiety

Product Name

Ro 60-0175 fumarate

Size

5.0mg; 10.0mg

Price

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Availability

2 Weeks

Description

Ro60-0175 is a potent and selective SR-2 agonist. It shows selectivity for the 5-HT2C subtype (pKi values are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). Ro60-0175 acts as a potent and selective agonist for both the 5-HT2B and 5-HT2C serotonin receptor subtypes, with good selectivity over the closely related 5-HT2A subtype, and little or no affinity at other receptors.

CAS Number

169675-09-6 (fumarate)

Chemical Formula

C15H16ClFN2O4

Molecular Weight

342.75

Elemental Analysis

C, 52.56; H, 4.71; Cl, 10.34; F, 5.54; N, 8.17; O, 18.67

Synonym

Ro 60-0175 fumarate; Ro60-0175; Ro-60-0175; Ro 60-0175; Ro600175; Ro-600175; Ro 600175;

IUPAC/Chemical Name

(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine fumarate

InChi Key

CEPHEXXZGQBXGT-XZTIXWOLSA-N

InChi Code

InChI=1S/C11H12ClFN2.C4H4O4/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15;5-3(6)1-2-4(7)8/h2-5,7H,6,14H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t7-;/m0./s1

SMILES Code

C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=C/C(=O)O)\C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO and water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.