Description
RG7713 is a vasopressin receptor 1A (V1a) antagonist. RG7713 increases biological motion orienting preference. RG7713 works within the vasopressin systemm, which is implicated in social cognition and social signaling deficits of ASD.
Chemical Formula
C25H28ClN3O2
Elemental Analysis
C, 68.56; H, 6.44; Cl, 8.09; N, 9.59; O, 7.31
Synonym
RG7713; RG 7713; RG-7713; RO5028442; RO 5028442; RO-5028442
IUPAC/Chemical Name
(6-chloro-1-(2-(dimethylamino)ethyl)-1H-indol-3-yl)(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)methanone
InChi Key
QZXVLRCMAHJVIP-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H28ClN3O2/c1-27(2)13-14-29-16-21(20-8-7-19(26)15-23(20)29)24(30)28-11-9-25(10-12-28)22-6-4-3-5-18(22)17-31-25/h3-8,15-16H,9-14,17H2,1-2H3
SMILES Code
CN(C)CCN1C(C=C(Cl)C=C2)=C2C(C(N3CCC4(C(C=CC=C5)=C5CO4)CC3)=O)=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO and chloroform
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO and chloroform
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001