Related Diseases
Depression
Size
100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g
Description
Rapastinel, also known as GLYX 13 and BV 102, is a monoclonal antibody-derived tetrapeptide that acts as a partial agonist at the glycine site of the N-methyl-D-aspartate (NMDA) receptor.
CAS Number
117928-94-6 (free base)
Chemical Formula
C18H31N5O6
Elemental Analysis
C, 52.29; H, 7.56; N, 16.94; O, 23.22
Synonym
GLYX-13; GLYX 13; GLYX13; BV-102; BV102; BV 102; TPPT-amide; Rapastinel
IUPAC/Chemical Name
(S)-1-(L-threonyl-L-prolyl)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)pyrrolidine-2-carboxamide
InChi Key
GIBQQARAXHVEGD-BSOLPCOYSA-N
InChi Code
InChI=1S/C18H31N5O6/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27)/t9-,10-,11+,12+,13+,14+/m1/s1
SMILES Code
C[C@@H](O)[C@@H](C(N)=O)NC([C@H]1N(C([C@H]2N(C([C@H]([C@H](O)C)N)=O)CCC2)=O)CCC1)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, DMF, and ethanol
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO, DMF, and ethanol
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001