Inquiry

* Name

Phone

* Email

* Services or Products of Interest

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

* Tick to confirm the Research Use Only (RUO) statement.

Protriptyline Hydrochloride

Inquiry

Specification

Cat. No.

SMD1099

Related Diseases

Depression

Product Name

Protriptyline Hydrochloride

Size

10.0mg; 50.0mg; 500.0mg

Price

Inquiry

Availability

2 Weeks

Description

Protriptyline Hydrochloride is a tricyclic secondary amine with antidepressant property. Protriptyline hydrochloride blocks the re-uptake of norepinephrine and serotonin by nerve terminals, thereby increasing available norepinephrine and serotonin. Protriptyline does not block dopamine transport but may have an indirect dopamine-facilitating effect through interactions of increased peri-synaptic abundance of norepinephrine, particularly in the cerebral cortex, where adrenergic terminals exceed dopaminergic terminals. This results in elevation of mood and behavioral activity. In addition, this agent exhibits anticholinergic activity.

CAS Number

1225-55-4 (HCl)

Chemical Formula

C19H22ClN

Molecular Weight

299.84

Elemental Analysis

C, 76.11; H, 7.40; Cl, 11.82; N, 4.67

Synonym

Protriptyline Hydrochloride; Concordin; Maximed; Triptyl; Protriptyline HCl; Triptil hydrochloride; Hydrochloride, Protriptyline; Odyssey Brand of Protriptyline Hydrochloride; Protriptyline; Protriptyline Hydrochloride ; Vivactil;

IUPAC/Chemical Name

3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine;hydrochloride

InChi Key

OGQDIIKRQRZXJH-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H

SMILES Code

CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.