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Pozanicline

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Specification

Cat. No.

SMD349

Related Diseases

Anxiety

Product Name

Pozanicline

Size

Customizable

Price

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Description

Pozanicline, also known as ABT-089, is a nootropic and neuroprotective agent under development for the treatment of ADHD. Pozanicline binds with high affinity subtype-selective to the α4β2 nicotinic acetylcholine receptors and has partial agonism to the α6β2 subtype, but not the α7 and α3β4 subtypes familiar to nicotine. Pozanicline has particularly low tendency to cause side effects compared to other drugs in the class.

CAS Number

161417-03-4

Chemical Formula

C11H16N2O

Exact Mass

192.1263

Molecular Weight

192.262

Elemental Analysis

C, 68.72; H, 8.39; N, 14.57; O, 8.32

Synonym

ABT-089; ABT 089; ABT089; A-87089; A-87089.0; Pozanicline

IUPAC/Chemical Name

2-Methyl-3-(2S-pyrrolidinylmethoxy)pyridine

InChi Key

YRVIKLBSVVNSHF-JTQLQIEISA-N

InChi Code

InChI=1S/C11H16N2O/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10/h3,5-6,10,13H,2,4,7-8H2,1H3/t10-/m0/s1

SMILES Code

CC1=NC=CC=C1OC[C@H]2NCCC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.