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PNU282987 HCl

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Specification

Cat. No.

SMD1654

Related Diseases

Schizophrenia

Product Name

PNU282987 HCl

Size

25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g

Price

Inquiry

Availability

2 Weeks

Description

PNU282987 is a drug that acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors. In animal studies, it shows nootropic effects, and derivatives may be useful in the treatment of schizophrenia, although PNU-282,987 is not suitable for use in humans because of excessive inhibition of the hERG antitarget.

CAS Number

123464-89-1 (HCl)

Chemical Formula

C14H18Cl2N2O

Molecular Weight

301.211

Elemental Analysis

C, 55.83; H, 6.02; Cl, 23.54; N, 9.30; O, 5.31

Synonym

PNU282987; PNU-282987; PNU 282987; PNU282,987; PNU-282,987; PNU 282,987; PNU282987 HCl; PNU282987 hydrochloride

IUPAC/Chemical Name

N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chloro-benzamide monohydrochloride

InChi Key

HSEQUIRZHDYOIX-ZOWNYOTGSA-N

InChi Code

InChI=1S/C14H17ClN2O.ClH/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17;/h1-4,10,13H,5-9H2,(H,16,18);1H/t13-;/m0./s1

SMILES Code

O=C(N[C@H]1CN2CCC1CC2)C3=CC=C(Cl)C=C3.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.