Piromelatine

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Piromelatine

Specification
Cat. No.
SMD1327
Related Diseases
Insomnia
Product Name
Piromelatine
Size
Customizable
Price
Inquiry
Description
Piromelatine, also known as NEU-P11, is a multimodal sleep drug under development by Neurim Pharmaceuticals. It is an agonist at melatonin MT1/MT2 and serotonin 5-HT1A/5-HT1D receptors. Pre-clinical studies showed antinociceptive, antihypertensive and cognitive benefits in rat disease models of pain, hypertension, and Alzheimer's disease.
CAS Number
946846-83-9
Chemical Formula
C17H16N2O4
Exact Mass
312.111
Molecular Weight
312.325
Elemental Analysis
C, 65.38; H, 5.16; N, 8.97; O, 20.49
Synonym
NEU-P11; NEU-P 11; NEU-P-11; Piromelatine
IUPAC/Chemical Name
N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-oxo-4H-pyran-2-carboxamide
InChi Key
PNTNBIHOAPJYDB-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H16N2O4/c1-22-13-2-3-15-14(9-13)11(10-19-15)4-6-18-17(21)16-8-12(20)5-7-23-16/h2-3,5,7-10,19H,4,6H2,1H3,(H,18,21)
SMILES Code
O=C(C1=CC(C=CO1)=O)NCCC2=CNC3=C2C=C(OC)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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