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Pipamperone HCl

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Specification

Cat. No.

SMD1661

Related Diseases

Schizophrenia

Product Name

Pipamperone HCl

Size

100.0mg

Price

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Availability

2 Weeks

Description

Pipamperone is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. Pipamperone acts as an antagonist of the 5-HT2A, 5-HT2B, 5-HT2C D2, D3, D4, α1-adrenergic, and α2-adrenergic receptors. It shows much higher affinity for the 5-HT2A and D4 receptors over the D2 receptor (15-fold in the case of the D4 receptor, and even higher in the case of the 5-HT2A receptor), being regarded as "highly selective" for the former two sites at low doses. Pipamperone has low and likely insignificant affinity for the H1 and mACh receptors, as well as for other serotonin and dopamine receptors.

CAS Number

2448-68-2 (HCl)

Chemical Formula

C21H32Cl2FN3O2

Exact Mass

447.1856

Molecular Weight

448.4044

Elemental Analysis

C, 56.25; H, 7.19; Cl, 15.81; F, 4.24; N, 9.37; O, 7.14

Synonym

Pipamperone, carpiperone; floropipamide; fluoropipamide, floropipamide hydrochloride; R4050, R-4050; R 4050; McN-JR-3345; Brand name: Dipiperon, Dipiperal, Piperonil, Piperonyl, and Propitan.

IUPAC/Chemical Name

1′-[4-(4-Fluorophenyl)-4-oxobutyl]-[1,4′-bipiperidine]-4′-carboxamide dihydrochloride

InChi Key

BMXXSXQVMCXGJM-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H

SMILES Code

O=C(C1(N2CCCCC2)CCN(CCCC(C3=CC=C(F)C=C3)=O)CC1)N.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.