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PHA-543613

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Specification

Cat. No.

SMD1634

Related Diseases

Schizophrenia

Product Name

PHA-543613

Size

5.0mg; 25.0mg

Price

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Availability

2 Weeks

Description

PHA-543613 acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.

CAS Number

478149-53-0

Chemical Formula

C15H17N3O2

Exact Mass

271.1321

Molecular Weight

271.32

Elemental Analysis

C, 66.40; H, 6.32; N, 15.49; O, 11.79

Synonym

PHA-543613; PHA 543613; PHA543613.

IUPAC/Chemical Name

(R)-N-(Quinuclidin-3-yl)furo(2,3-C)pyridine-5-carboxamide

InChi Key

IPKZCLGGYKRDES-ZDUSSCGKSA-N

InChi Code

InChI=1S/C15H17N3O2/c19-15(12-7-11-3-6-20-14(11)8-16-12)17-13-9-18-4-1-10(13)2-5-18/h3,6-8,10,13H,1-2,4-5,9H2,(H,17,19)/t13-/m0/s1

SMILES Code

O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.