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PHA 543613 hydrochloride

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Specification

Cat. No.

SMD1640

Related Diseases

Schizophrenia

Product Name

PHA 543613 hydrochloride

Size

10.0mg

Price

Inquiry

Availability

2 Weeks

Description

PHA-543613 hydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.

CAS Number

1586767-92-1 (HCl)

Chemical Formula

C15H18ClN3O2

Molecular Weight

307.78

Elemental Analysis

C, 58.54; H, 5.90; Cl, 11.52; N, 13.65; O, 10.40

Synonym

PHA 543613 hydrochloride; PHA543613 hydrochloride; PHA-543613 hydrochloride, PHA 543613 HCl;

IUPAC/Chemical Name

(R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide hydrochloride

InChi Key

YMTPSZUBRSEWNY-ZOWNYOTGSA-N

InChi Code

InChI=1S/C15H17N3O2.ClH/c19-15(12-7-11-3-6-20-14(11)8-16-12)17-13-9-18-4-1-10(13)2-5-18;/h3,6-8,10,13H,1-2,4-5,9H2,(H,17,19);1H/t13-;/m0./s1

SMILES Code

O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.