Related Diseases
Schizophrenia
Product Name
PHA 543613 dihydrochloride
Description
PHA-543613 dihydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.
CAS Number
478148-58-2 (2HCl)
Chemical Formula
C15H19Cl2N3O2
Elemental Analysis
C, 52.34; H, 5.56; Cl, 20.60; N, 12.21; O, 9.30
Synonym
PHA 543613 dihydrochloride; PHA-543613 dihydrochloride; PHA543613 dihydrochloride; PHA 543613. 2HCl;
IUPAC/Chemical Name
(R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide dihydrochloride
InChi Key
USJDQOUQSDDWPO-GXKRWWSZSA-N
InChi Code
InChI=1S/C15H17N3O2.2ClH/c19-15(12-7-11-3-6-20-14(11)8-16-12)17-13-9-18-4-1-10(13)2-5-18;;/h3,6-8,10,13H,1-2,4-5,9H2,(H,17,19);2*1H/t13-;;/m0../s1
SMILES Code
O=C(C1=CC2=C(OC=C2)C=N1)N[C@H]3CN4CCC3CC4.[H]Cl.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001