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PF-06372865

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Specification

Cat. No.

SMD344

Related Diseases

Anxiety

Product Name

PF-06372865

Size

Customizable

Price

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Description

PF-06372865, also known as Darigabat, is a potent α2/3/5 subunit selective GABAa positive allosteric modulator.

CAS Number

1614245-70-3

Chemical Formula

C22H21FN4O3S

Exact Mass

440.1318

Molecular Weight

440.49

Elemental Analysis

C, 59.99; H, 4.81; F, 4.31; N, 12.72; O, 10.90; S, 7.28

Synonym

PF06372865; PF 06372865; PF-06372865; Darigabat

IUPAC/Chemical Name

7-Ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine

InChi Key

PTTQXDBPTFOCMT-UHFFFAOYSA-N

InChi Code

InChI=1S/C22H21FN4O3S/c1-4-27-13-24-21-18(12-25-26-22(21)27)14-6-9-19(23)17(10-14)16-8-7-15(11-20(16)30-3)31(28,29)5-2/h6-13H,4-5H2,1-3H3

SMILES Code

COC1=CC(S(=O)(CC)=O)=CC=C1C2=C(F)C=CC(C3=C4C(N(CC)C=N4)=NN=C3)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.