PF-03463275

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PF-03463275

Specification
Cat. No.
SMD1646
Related Diseases
Schizophrenia
Product Name
PF-03463275
Size
Customizable
Price
Inquiry
Description
PF-03463275 is an orally available, CNS-penetrant inhibitor of SLC6A9, the GlyT1 glycine transporter, developed for potential anti-schizophrenia activity.
CAS Number
1173177-11-1
Chemical Formula
C19H22ClFN4O
Exact Mass
376.1466
Molecular Weight
376.86
Elemental Analysis
C, 60.56; H, 5.88; Cl, 9.41; F, 5.04; N, 14.87; O, 4.25
Synonym
PF-03463275; PF03463275; PF 03463275; PF-3463275; PF3463275; PF 3463275; KB-79869; KB 79869.
IUPAC/Chemical Name
N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-[[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]imidazole-4-carboxamide
InChi Key
KYLOBHXXQOZRKK-YIONKMFJSA-N
InChi Code
InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15?
SMILES Code
O=C(C1=CN(C)C=N1)N(CC2=CC=C(F)C(Cl)=C2)CC3[C@@]4([H])CN(C)C[C@@]34[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001
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