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PF-03463275

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Specification

Cat. No.

SMD1646

Related Diseases

Schizophrenia

Product Name

PF-03463275

Size

Customizable

Price

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Description

PF-03463275 is an orally available, CNS-penetrant inhibitor of SLC6A9, the GlyT1 glycine transporter, developed for potential anti-schizophrenia activity.

CAS Number

1173177-11-1

Chemical Formula

C19H22ClFN4O

Exact Mass

376.1466

Molecular Weight

376.86

Elemental Analysis

C, 60.56; H, 5.88; Cl, 9.41; F, 5.04; N, 14.87; O, 4.25

Synonym

PF-03463275; PF03463275; PF 03463275; PF-3463275; PF3463275; PF 3463275; KB-79869; KB 79869.

IUPAC/Chemical Name

N-[(3-chloro-4-fluorophenyl)methyl]-1-methyl-N-[[(1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-6-yl]methyl]imidazole-4-carboxamide

InChi Key

KYLOBHXXQOZRKK-YIONKMFJSA-N

InChi Code

InChI=1S/C19H22ClFN4O/c1-23-7-13-14(8-23)15(13)9-25(19(26)18-10-24(2)11-22-18)6-12-3-4-17(21)16(20)5-12/h3-5,10-11,13-15H,6-9H2,1-2H3/t13-,14+,15?

SMILES Code

O=C(C1=CN(C)C=N1)N(CC2=CC=C(F)C(Cl)=C2)CC3[C@@]4([H])CN(C)C[C@@]34[H]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.