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Panamesine

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Specification

Cat. No.

SMD1619

Related Diseases

Schizophrenia

Product Name

Panamesine

Size

5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg

Price

Inquiry

Availability

2 Weeks

Description

Panamesine is a sigma receptor antagonist that was under development by Merck as a potential antipsychotic for the treatment of schizophrenia in the 1990s but was never marketed. It is a selective antagonist of both sigma receptor subtypes, the σ₁ and σ₂ receptors.

CAS Number

139225-22-2

Chemical Formula

C23H26N2O6

Exact Mass

426.1791

Molecular Weight

426.47

Elemental Analysis

C, 64.78; H, 6.15; N, 6.57; O, 22.51

Synonym

Panamesine

IUPAC/Chemical Name

(5S)-5-((4-Hydroxy-4-(3,4-(methylenedioxy)phenyl)piperidino)methyl)-3-(p-methoxyphenyl)-2-oxazolidinone.

InChi Key

NINYZUDVKTUKIA-IBGZPJMESA-N

InChi Code

InChI=1S/C23H26N2O6/c1-28-18-5-3-17(4-6-18)25-14-19(31-22(25)26)13-24-10-8-23(27,9-11-24)16-2-7-20-21(12-16)30-15-29-20/h2-7,12,19,27H,8-11,13-15H2,1H3/t19-/m0/s1

SMILES Code

O=C1O[C@@H](CN2CCC(C3=CC(OCO4)=C4C=C3)(O)CC2)CN1C5=CC=C(OC)C=C5

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.