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Org-6906

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Specification

Cat. No.

SMD1062

Related Diseases

Depression

Product Name

Org-6906

Size

Customizable

Price

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Description

Org-6906 is a dual of monoamine uptake inhibitor and α2 adrenoceptor antagonist potentially for the treatment. Org-6906 facilitated potassium-stimulated release of noradrenaline from slices of cortex, displaced [3H]rauwolscine and [3H]dihydroergocryptine from their binding sites but only weakly blocked alpha 1-adrenoceptors. The alpha 2-adrenolytic properties were also apparent in behavioural interaction models. The compound antagonized the sleep-inducing effects of clonidine in chicks and mice and it antagonized the mydriasis induced by clonidine in the rat.

CAS Number

67384-25-2

Chemical Formula

C13H16ClN

Molecular Weight

221.728

Elemental Analysis

C, 70.42; H, 7.27; Cl, 15.99; N, 6.32

Synonym

Org-6906; Org 6906; Org6906; Org-6906 free

IUPAC/Chemical Name

5,8,9,10-tetrahydro-5,9-methanobenzo[8]annulen-8-amine hydrochloride

InChi Key

FTKXWCQSVJPWPZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C13H15N.ClH/c14-13-6-5-10-8-11(13)7-9-3-1-2-4-12(9)10;/h1-6,10-11,13H,7-8,14H2;1H

SMILES Code

NC1C2CC3=CC=CC=C3C(C2)C=C1.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.