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ORG-12962 hydrochloride

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Specification

Cat. No.

SMD323

Related Diseases

Anxiety

Product Name

ORG-12962 hydrochloride

Size

5.0mg; 10.0mg; 25.0mg; 50.0mg

Price

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Availability

2 Weeks

Description

ORG-12962 hydrochloride is an agonist of the serotonin (5-HT) receptor subtype 5-HT2C that is selective for 5-HT2C over 5-HT2A and 5-HT2B receptors. ORG-12962 HCl has anti-aversive effects in a rat model of panic anxiety induced by dorsolateral periaqueductal gray matter (dPAG) stimulation.

CAS Number

210821-63-9

Chemical Formula

C10H12Cl2F3N3

Exact Mass

301.036

Molecular Weight

302.1222

Elemental Analysis

C, 39.76; H, 4.00; Cl, 23.47; F, 18.86; N, 13.91

Synonym

ORG-12962 HCl; Ro 44-6956

IUPAC/Chemical Name

1-[6-chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine, monohydrochloride

InChi Key

FVDILXYXZAAJOS-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H11ClF3N3.ClH/c11-9-7(10(12,13)14)1-2-8(16-9)17-5-3-15-4-6-17;/h1-2,15H,3-6H2;1H

SMILES Code

ClC1=NC(N2CCNCC2)=CC=C1C(F)(F)F.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.