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Norfluoxetine-d5 HCl

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Specification

Cat. No.

SMD1086

Related Diseases

Depression

Product Name

Norfluoxetine-d5 HCl

Size

1.0mg; 5.0mg

Price

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Availability

2 Weeks

Description

Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewater effluent.

CAS Number

1185132-92-6

Chemical Formula

C16H12D5ClF3NO

Exact Mass

336.1265

Molecular Weight

336.7937

Elemental Analysis

C, 57.06; H, 6.58; Cl, 10.53; F, 16.92; N, 4.16; O, 4.75

Synonym

Norfluoxetine-d5 HCl; Norfluoxetine d5 HCl; Norfluoxetine-d5 hydrochloride; Norfluoxetine d5 hydrochloride; Desmethylfluoxetine-d5; Desmethylfluoxetine d5;

IUPAC/Chemical Name

3-phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1,1,2,2,3-d5-1-amine hydrochloride

InChi Key

GMTWWEPBGGXBTO-KDPCSTGBSA-N

InChi Code

InChI=1S/C16H16F3NO.ClH/c17-16(18,19)13-6-8-14(9-7-13)21-15(10-11-20)12-4-2-1-3-5-12;/h1-9,15H,10-11,20H2;1H/i10D2,11D2,15D;

SMILES Code

FC(F)(C1=CC=C(OC([2H])(C([2H])(C([2H])(N)[2H])[2H])C2=CC=CC=C2)C=C1)F.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).

HS Tariff Code

2934.99.9001

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.