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Project Description

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NGFR/p75NTR Protein, Human, Recombinant (hFc Tag), HPLC-verified

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Specification

Cat. No.

NSC380

Category

Neural Stem Cell Growth Factors

Product Type

Proteins

Product Name

NGFR/p75NTR Protein, Human, Recombinant (hFc Tag), HPLC-verified

Size

100 µg

Price

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Synonyms

CD271 Protein, Human; Gp80-LNGFR Protein, Human; p75(NTR) Protein, Human; p75NTR Protein, Human; TNFRSF16 Protein, Human

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Activity

Testing in progress

Protein Construction

A DNA sequence encoding the human NGFR (P08138) extracellular domain (Met 1-Asn 250) was fused with the Fc region of human IgG1 at the C-terminus.

Accession#

P08138

Expressed Host

HEK293 Cells

Species

Human

Predicted N Terminal

Lys 29

Molecule Mass

The secreted recombinant human NGFR/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 463 amino acids and has a predicted molecular mass of 50.6 kDa. The apparent molecular mass of rhNGFR/Fc monomer is approximately 70-80 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Formulation

Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Reconstitution

A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.

Related Pathways

Death Receptor Signaling

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.