Related Diseases
Schizophrenia
Product Name
Neuromedin N
Description
Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin. It binds to neurotensin receptors to regulate guinea pig intestinal smooth muscle contraction. It also produces hypotension in rats and induces hypothermia following central administration in rats in vivo.
Chemical Formula
C38H63N7O8
Elemental Analysis
C, 61.19; H, 8.51; N, 13.14; O, 17.16
Synonym
Neuromedin N; Neuromedin-N; KIPYIL; Lys-Ile-Pro-Tyr-Ile-Leu; H-Lys-Ile-Pro-Tyr-Ile-Leu-OH;
IUPAC/Chemical Name
L-lysyl-L-isoleucyl-L-prolyl-L-tyrosyl-L-isoleucyl-L-leucine
InChi Key
RZMLVIHXZGQADB-YLUGYNJDSA-N
InChi Code
InChI=1S/C38H63N7O8/c1-7-23(5)31(36(50)42-29(38(52)53)20-22(3)4)43-34(48)28(21-25-14-16-26(46)17-15-25)41-35(49)30-13-11-19-45(30)37(51)32(24(6)8-2)44-33(47)27(40)12-9-10-18-39/h14-17,22-24,27-32,46H,7-13,18-21,39-40H2,1-6H3,(H,41,49)(H,42,50)(H,43,48)(H,44,47)(H,52,53)/t23-,24-,27-,28-,29-,30-,31-,32-/m0/s1
SMILES Code
O=C(N[C@@H]([C@@H](C)CC)C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)[C@H](CCCCN)N
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
HS Tariff Code
2934.99.9001